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4-Nitrobenzoic acid used as an intermediate for bulk drugs especially in the manufacturing of folic acid and in the manufacturing of PABA, DABA & dye intermediate.
Hyouk Soo Han; Sang Woo Han; Chang Hwan Kim; Kwan Kim. Adsorption and reaction of 4-Nitrobenzoic acid on ω-functionalized alkanethiol monolayers on powdered silver:? Infrared and raman spectroscopy study. Langmuir. 2000, 16, (3),1149-1157
Hyouk Soo; Han Chang; Hwan Kim; Kwan Kim. Diffuse Reflectance Infrared Spectra of 4-Nitrobenzoic Acid and 4-Cyanobenzoic Acid Self-Assembled on Fine Silver Particles. Applied Spectroscopy. 1998, 52, (8),1047-1052
Selective reduction of the carboxyl group to the alcohol can be achieved in 94% yield using Benzyltriethylammonium borohydride, B24952, in combination with TMS chloride. Esters are unaffected under these conditions: Synth. Commun., 20, 907 (1990). See also, J. Chem. Soc., Chem. Commun., 903 (1989).
Gefahrenhinweise (EU): H302-H319
Harmful if swallowed. Causes serious eye irritation.
Wear eye/face protection. Wash thoroughly after handling. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: If eye irritation persists: Get medical advice/attention. Dispose of contents/container in accordance with local/regional/national/international regulations.