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79-43-6 - Dichloroacetic acid, 99% - A14740 - Alfa Aesar

A14740 Dichloroacetic acid, 99%

CAS-Nummer
79-43-6
Synonyme

Größe Preis ($) Menge Verfügbarkeit
100g 19,80
500g 38,97
2500g 121,54
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

Dichloroacetic acid, 99%

MDL
MFCD00004223
EINECS
201-207-0

Chemische Eigenschaften

Formel
Cl2CHCO2H
Molmasse
128.94
Schmelzpunkt
9-11°
Siedepunkt
192-194°
Flammpunkt
>110°(230°F)
Dichte
1.564
Brechungsindex
1.4620
Sensitivität
Hygroscopic
Löslichkeit
Miscible with water, ethanol, diethyl ether, n-octanol and acetone.

Anwendungen

Dichloroacetic acid salts are used as drugs due to its inhibition of the enzyme pyruvate dehydrogenase kinase. It is also employed to stem the production of lactic acid to treat lactic acidosis. It is clinically essential in children to treat lactic acidosis.

Bemerkungen

Incompatible with strong oxidizing agents, strong bases and strong reducing agents.

Literaturverweise

Moderately strong acid which has been recommended for the catalysis of mixed acetal formation by reaction of alcohols with Ethyl­ vinyl­ ether, A15691 . Has also been used as an acid catalyst and deprotecting agent in various other applications including peptide synthesis.

Ding, Y.; Zhu, J.; Ji, D.; Cao, Y.; Ling, X.; Chen, W. Enhancing adsorption efficiency of dichloroacetic acid onto mesoporous carbons: Procedure optimization, mechanism and characterization. J. Colloid Interface Sci. 2015, 452, 134-140.

Scialdone, O.; Galia, A.; Sabatino, S.; Mira, D.; Amatore, C. Electrochemical Conversion of Dichloroacetic Acid to Chloroacetic Acid in a Microfluidic Stack and in a Series of Microfluidic Reactors. Chem. Electro. Chem. 2015, 2 (5), 684-690.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H314-H400

Causes severe skin burns and eye damage. Very toxic to aquatic life.

Sicherheitshinweise: P260-P273-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Avoid release to the environment. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or doctor/physician. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,3050
Beilstein
1098596
Gefahrenklasse
8
Verpackungsgruppe
II
Harmonized Tariff Code
2915.40
TSCA
Yes
RTECS
AG6125000

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