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2- Chloropyridine is used as an intermediate chemical in the production of various pyrithione, for use in cosmetics, personal care products and pharmaceutical products.
Sabine Choppin.; Philippe Gros.; Yves For. Unusual C-6 Lithiation of 2-Chloropyridine-Mediated by BuLi-Me2N(CH2)2OLi. New Access to 6-Functional-2-chloropyridines and Chloro-bis-heterocycles. Org. Lett. 2002, 2, (6), 803-805.
Meriç Bakiler.; I.V. Maslov.; Sevim Akyüzc.Theoretical study of the vibrational spectra of 2-chloropyridine metal complexes. I. Calculation and analysis of the IR spectrum of 2-chloropyridine. Journal of Molecular Structure. 1999, 475, (1), 83-92.
Reaction with the unimetal suberbase complex formed from 2 mol of n-BuLi and I mol of 2-(Dimethylamino)ethanol, B23616, in hexane, gives products resulting from apparent metallation at the 6-position, providing useful access to 6-functionalized 2-chloropyridines: Org. Lett., 2, 803 (2000). See also 2-Methoxypyridine, A13675, for a similar effect.
Gefahrenhinweise (EU): H227-H301-H310-H330-H315-H318-H335
Combustible liquid. Toxic if swallowed. Fatal in contact with skin. Fatal if inhaled. Causes skin irritation. Causes serious eye damage. May cause respiratory irritation.
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.