4-Bromoaniline is used as a precursor in the production of azo dyes and dihydroquinazolines. It is also used as carbon and nitrogen supplement in the culture medium of Moraxella sp. strain G. Further, it is employed in the preparation of para-bromobiphenyl through Gomberg-Bachmann reaction. In addition to this, it is used as a building block in the preparation or pharmaceutical and organic compounds.
Gao, W. Synthesis and Structure Analysis of N-diphenylphosphoryl-4-bromoaniline. Mol. Cryst. Liq. Cryst. 2015, 609 (1), 155-160.
Štrukil, V.; Gracin, D.; Magdysyuk, O. V.; Dinnebier, R. E.; Frišči?, T. Trapping Reactive Intermediates by Mechanochemistry: Elusive Aryl N-Thiocarbamoylbenzotriazoles as Bench-Stable Reagents. Angew. Chem. Int. Ed. 2015, 54 (29), 8440-8443.
Gefahrenhinweise (EU): H302-H311-H332-H315-H319-H373
Harmful if swallowed. Toxic in contact with skin. Harmful if inhaled. Causes skin irritation. Causes serious eye irritation. May cause damage to organs through prolonged or repeated exposure.
Wear protective gloves/clothing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or if you feel unwell: Immediately call a POISON CENTER/doctor IF ON SKIN: Wash with plenty of water.