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3934-20-1 - 2,4-Dichloropyrimidine, 98+% - A15131 - Alfa Aesar

A15131 2,4-Dichloropyrimidine, 98+%

CAS-Nummer
3934-20-1
Synonyme

Größe Preis ($) Menge Verfügbarkeit
5g 41,13
10g 59,76
50g 240,30
250g 851,20
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2,4-Dichloropyrimidine, 98+%

MDL
MFCD00006061
EINECS
223-508-6

Chemische Eigenschaften

Formel
C4H2Cl2N2
Molmasse
148.98
Schmelzpunkt
57-62°
Siedepunkt
101°/23mm
Sensitivität
Moisture Sensitive
Löslichkeit
Soluble in water (partly), methanol, chloroform, and ethyl acetate.

Anwendungen

2,4-Dichloropyrimidine is used in the synthesis of medicinally important 4-aryl-5-pyrimidinylimidazoles. It undergoes effective one-pot, regioselective double Suzuki coupling reaction to yield diarylated pyrimidines.

Bemerkungen

Moisture Sensitive. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Literaturverweise

Xiaohu Deng.; Neelakandha S. Mani. An Efficient Route to 4-Aryl-5-pyrimidinylimidazoles via Sequential Functionalization of 2,4-Dichloropyrimidine. Org. Lett. 2006, 8, (2), 269-272.

Zhi-Hui Peng.; Michel Journet.; Guy Humphrey. A Highly Regioselective Amination of 6-Aryl-2,4-dichloropyrimidine. Org. Lett. 2006, 8, (3), 395-398.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Beilstein
110911
Harmonized Tariff Code
2933.59
TSCA
Yes

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