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Uridine plays a vital role in the glycolysis pathway of galactose. It is used as a precursor in the production of CDP-choline. It is an important nutrient and widely used as a dietary supplement. It improves brain cholinergic functions and hepatic mitochondrial function in certain liver toxins. It plays a major role in pain physiology and brain energy utilization to maintain ATP production under restricted oxygen conditions.
Heuberger, B. D.; Pal, A.; Del Frate, F.; Topkar, V. V.; Szostak, J. W. Replacing Uridine with 2-Thiouridine Enhances the Rate and Fidelity of Nonenzymatic RNA Primer Extension. J. Am. Chem. Soc. 2015, 137 (7), 2769-2775.
L Ipata, P.; Pesi, R. Metabolic Regulation of Uridine in the Brain. Curr Metabolomics 2015, 3 (1), 4-9.