Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

569-58-4 - Aluminon - Aurintricarboxylic acid triammonium salt - A15401 - Alfa Aesar

A15401 Aluminon

CAS-Nummer
569-58-4
Synonyme
Aurintricarboxylic acid triammonium salt

Größe Preis ($) Menge Verfügbarkeit
10g 18,75
50g 60,26
250g 229,04
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

Aluminon

MDL
MFCD00040925
EINECS
209-319-1

Chemische Eigenschaften

Formel
C22H23N3O9
Molmasse
473.44
Schmelzpunkt
220-225° dec.
Löslichkeit
Soluble in water(800g/L).

Anwendungen

It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells. Aurintricarboxylic acid inhibits apoptosis in many cell types.

Bemerkungen

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Literaturverweise

R G González,; R S Haxo,; T Schleich. Mechanism of action of polymeric aurintricarboxylic acid, a potent inhibitor of protein--nucleic acid interactions. Biochemistry (Washington). 1980, 19 (18),4299-4303.

Y Benchokroun,; J Couprie,; A K Larsen. Aurintricarboxylic acid, a putative inhibitor of apoptosis, is a potent inhibitor of DNA topoisomerase II in vitro and in Chinese hamster fibrosarcoma cells. Biochemical Pharmacology. 1995, 49(3), 305-313.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319

Causes skin irritation. Causes serious eye irritation.

Sicherheitshinweise: P280-P264-P305+P351+P338-P362-P321-P332+P313-P337+P313-P302+P352

Wear protective gloves/protective clothing/eye protection/face protection. Wash thoroughly after handling. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Take off contaminated clothing and wash before reuse. Specific treatment (see label). If skin irritation occurs: Get medical advice/attention. If eye irritation persists: IF ON SKIN: Wash with plenty of soap and water.

Weitere Referenzen

Merck
14,322
Harmonized Tariff Code
2918.99
TSCA
Yes
RTECS
GU4800000

Empfohlen

  • A10180

    n-Propyl 4-hydroxybenzoate, 99+%
  • A10190

    Ammonium thiosulfate, 98+%
  • A10337

    4-Methylumbelliferone, 97%
  • A16345

    Lead(II) nitrate, 99%
  • 00010

    Aluminum powder, -40+325 mesh, 99.8% (metals basis)

Kürzlich angesehen

Chemikalien

Life science

Metalle und Stoffe

Katalysatoren

Forschungs- und Laborbedarf