I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.
Reactant involved in they synthesis of biologically active molecules including small molecule ligands for the Stat3 SH2 domain, aryldisulfonamides with antibacterial activity, quinazoline analogs for the treatment of Gaucher disease, 17β-HSD2 inhibitors for the treatment of osteoporosis, isoindoline-5-propenehydroxamates for use as histone deactylase inhibitors.
Wen-Hsing Lin; Shu-Yi Hsieh; Shih-Chieh Yen; Chiung-Tong Chen; Teng-Kuang Yeh; Tsu Hsu; Cheng-Tai Lu; Ching-Ping Chen; Chun-Wha Chen; Ling-Hui Chou; Yu-Lin Huang; An-Huei Cheng; Yun-I Chang; Ya-Ju Tseng; Kuei-Rong Yen; Yu-Sheng Chao; John T.-A. Hsu; Weir-Torn Jiaang. Discovery and evaluation of 3-phenyl-1H-5-pyrazolylamine-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3). Bioorganic & Medicinal Chemistry. 2011, 19 (14), 4173-4182.
Brent D G Page; Steven Fletcher; Peibin Yue; Zhihua Li; Xiaolei Zhang; Sumaiya Sharmeen; Alessandro Datti; Jeffrey L Wrana; Suzanne Trudel; Aaron D Schimmer; James Turkson; Patrick T Gunning. Identification of a non-phosphorylated, cell permeable, small molecule ligand for the Stat3 SH2 domain. Bioorganic & Medicinal Chemistry Letters. 2011, 21 (18), 5605-5609.
Gefahrenhinweise (EU): H314-H318
Causes severe skin burns and eye damage. Causes serious eye damage.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.