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289-95-2 - Pyrimidine, 99% - A15534 - Alfa Aesar

A15534 Pyrimidine, 99%

CAS-Nummer
289-95-2
Synonyme

Größe Preis ($) Menge Verfügbarkeit
1g 29,56
5g 91,05
25g 285,60
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

Pyrimidine, 99%

MDL
MFCD00006059
EINECS
206-026-0

Chemische Eigenschaften

Formel
C4H4N2
Molmasse
80.09
Schmelzpunkt
20-22°
Siedepunkt
123-124°
Flammpunkt
31°(87°F)
Dichte
1.016
Brechungsindex
1.5040
Sensitivität
Hygroscopic
Löslichkeit
Fully miscible in water.

Anwendungen

Used in the synthesis and discovery of antiviral medication, such as in the case of HIV and HSV. Also used in the synthesis of potent inhibitors of 15-lipoxygenase in the reduction of the release of leukotrienes. And in ithe production of RNA and DNA, proteins and starches, the regulation of enzymes and cell signaling.

Bemerkungen

Hygroscopic. Store under inert gas. Store away from oxidizing agents, water/ moisture.

Literaturverweise

Vilhelm A. Bohr; Charles Allen Smith; Diane S. Okumoto; Philip C. Hanawalt. DNA repair in an active gene: Removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall. Cell. 1985, 40 (2), 359-369.

R.B. Setlow; W.L. Carrier. Pyrimidine dimers in ultraviolet-irradiated DNA's. Journal of Molecular Biology. 1996, 17 (1), 237-254.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H226

Flammable liquid and vapour.

Sicherheitshinweise: P210-P280-P240-P241-P233-P242-P243-P303+P361+P353-P403+P235-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Wear protective gloves/protective clothing/eye protection/face protection. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. Keep container tightly closed. Use only non-sparking tools. Take precautionary measures against static discharge. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. Store in a well-ventilated place. Keep cool. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,7987
Beilstein
103894
Gefahrenklasse
3
Verpackungsgruppe
III
Harmonized Tariff Code
2933.59
TSCA
Yes
RTECS
UV6263000

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