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Methyl phenylacetate is utilized for partition coefficient measurement experiments. It is mainly used in the flavor industry and in perfumes to impart honey scents. Further, it acts as a precursor to prepare synthetic perfumes. It acts as an acylating agent and involved in the enantioselective acylation of beta-lactam intermediate using penicillin G amidase.
Ramachandran, P. V.; Chanda, P. B. Overriding effect of temperature over reagent and substrate size for boron-mediated aldol reaction of methyl phenylacetate. Tetrahedron Lett. 2013, 54 (44), 5886-5888.
Ramachandran, P. V.; Chanda, P. B. Solvent-or Temperature-Controlled Diastereoselective Aldol Reaction of Methyl Phenylacetate. Org. lett. 2012, 14 (17), 4346-4349.
Müller, S. T.; Murat, A.; Maillos, D.; Lesimple, P.; Hellier, P.; Wirth, T. Rapid Generation and Safe Use of Carbenes Enabled by a Novel Flow Protocol with In-line IR spectroscopy. Chem. Eur. J. 2012, 21 (19), 7016-7020.
Gefahrenhinweise (EU): H227-H303
Combustible liquid. May be harmful if swallowed.
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Wear protective gloves and eye/face protection. Call a POISON CENTER/doctor if you feel unwell. In case of fire: Use for extinction: CO2, powder or water spray. Store in a well-ventilated place. Keep cool. Dispose of contents/container in accordance with local/regional/national/international regulations.