I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.
(1-Ethoxycarbonylethylidene)triphenylphosphorane is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals. Its also a Horner-Wadsworth-Emmons reagent. It can be used for olefination. It can also be utilized for the synthesis of more complex compounds, such as (29S,37S)-isomer of malevamide E, a potent ion-channel inhibitor.
Yasumasa Koyama; Yuichi Fukakusa; Nobuo Kyomura; Saburo Yamagishi; Tadashi Arai. The structure of luteoreticulin, a nitro-containing metabolite of streptomyces luteoreticuli. Tetrahedron Letters. 1969, 10 (5), 355-358.
Vlark F. Beatty; Clive Jennings-White; and Mitchell A. Avery. Stereocontrolled synthesis of (2S,3S,8S,9S,4E,6E)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoic acid (Adda), the amino acid characteristic of microcystins and nodularin. J. Chem. Soc., Perkin Trans. 1. 1992, (13), 1637-1641.
Stable ylide which reacts with aldehydes to give ß-substituted methacrylic esters. See Appendix 1.
With acyl halides, gives allenic esters: Helv. Chim. Acta, 63, 438 (1980); Org. Synth. Coll., 7, 232 (1990):
Reacts with the carbonyl group of succinic anhydride giving an intermediate useful in the synthesis of 2,2-dialkylcyclopentane-1,3-diones: Synthesis, 845 (1986):