A15733 (Formylmethyl)triphenylphosphonium chloride, 98+%
SDS
| Stock No. | Größe | Preis ($) | Menge | Verfügbarkeit |
|---|---|---|---|---|
| A15733-09 | 10g | 27,70 |
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| A15733-18 | 50g | 104,00 |
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| A15733-22 | 100g | 188,00 |
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(Formylmethyl)triphenylphosphonium chloride, 98+%
Chemische Eigenschaften
Anwendungen
(Formylmethyl)triphenylphosphonium Chloride is a useful Wittig reagent. Used as a reactant for Hydroazidation reactions in preparation of a-azido alcohols, Preparation of prodrug (2-hydroxyamino-vinyl)-triphenyl-phosphonium (HVTP) inhibitor of peroxidase activity and apoptosis and Intramolecular [4 + 3] cycloaddition reactions.
Bemerkungen
Literaturverweise
Klaus Banert; Christian Berndt; Samia Firdous; Manfred Hagedorn; Young-Hyuk Joo; Tobias Rüffer; Heinrich Lang. Extremely simple but long overlooked: generation of α-azido alcohols by hydroazidation of aldehydes. Angewandte Chemie. International edition in English. 2010, 49 (52), 10206-10209.
Detcho A Stoyanovsky; Irina I Vlasova; Natalia A Belikova; Alexandr Kapralov; Vladimir Tyurin; Joel S Greenberger; Valerian E Kagan. Activation of NO donors in mitochondria: peroxidase metabolism of (2-hydroxyamino-vinyl)-triphenyl-phosphonium by cytochrome c releases NO and protects cells against apoptosis. FEBS Letters. 2008, 582 (5), 725-728.
Undergoes the Wittig reaction with aldehydes to give acrylic aldehydes either in the presence of base or by prior conversion to the phosphorane. For references see (Formylmethylene)triphenylphosphorane, A11709.
GHS Gefahren- und Sicherheitshinweise
Gefahrenhinweise (EU): H302-H318
Harmful if swallowed. Causes serious eye damage.
Sicherheitshinweise: P280i-P264-P305+P351+P338-P310a-P301+P312a-P501a
Wear eye/face protection. Wash thoroughly after handling. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Dispose of contents/container in accordance with local/regional/national/international regulations.
