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505-66-8 - Homopiperazine, 98% - 1,4-Diazacycloheptane - Hexahydro-1,4-diazepine - A15751 - Alfa Aesar

A15751 Homopiperazine, 98%

CAS-Nummer
505-66-8
Synonyme
1,4-Diazacycloheptane
Hexahydro-1,4-diazepine

Größe Preis ($) Menge Verfügbarkeit
25g 40,17
100g 121,50
500g 448,80
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Homopiperazine, 98%

MDL
MFCD00006933
EINECS
208-016-1

Chemische Eigenschaften

Formel
C5H12N2
Molmasse
100.17
Schmelzpunkt
38-44°
Siedepunkt
168-170°
Flammpunkt
64°(147°F)
Dichte
0.95
Sensitivität
Air Sensitive & Hygroscopic
Löslichkeit
Soluble in water.

Anwendungen

Homopiperazine is used to prepare 1,4-bis-(2-thiazolyl)-1,4-diazacycloheptane by reacting with 2-bromo-thiazole. It acts as an intermediate for repaglinide and fasudil hydrochloride. It is also used in the preparation of potent H3 receptor antagonists, which is used for the treatment of neurodegenerative conditions. Further, it is used in vesicant, cosmetic, emulsifier and energetic material. It acts as a corrosion inhibitor for iron. In pharmaceuticals, it is employed as antipyretic and reducing blood sugar, adiposity, calm, antipsychotic and anti-nervous.

Bemerkungen

Hygroscopic. Air sensitive. Incompatible with strong oxidizing agents and strong acids.

Literaturverweise

Keypour, H.; Rezaeivala, M.; Mirzaei-Monsef, M.; Sayin, K.; Dilek, N.; Unver, H. Synthesis and characterization of Co(II), Ni(II), Cu(II) and Zn(II) complexes with a new homopiperazine macrocyclic Schiff base ligand. Inorg. Chim. Acta 2015, 432, 243-249.

Vinodh, R.; Bhagiyalakshmi, M.; Hemalatha, P.; Ganesh, M.; Peng, M. M.; Palanichamy, M.; Cha, W. S.; Jang, H. T. Homopiperazine Grafted Mesoporous Silicas from Rice Husk Ash for CO2 Adsorption. J. Nanosci. Nanotechnol. 2014, 14 (6), 4639-4648.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H314-H318-H312-H303

Causes severe skin burns and eye damage. Causes serious eye damage. Harmful in contact with skin. May be harmful if swallowed.

Sicherheitshinweise: P280-P305+P351+P338-P309-P310

Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or if you feel unwell: Immediately call a POISON CENTER or doctor/physician.

Weitere Referenzen

Beilstein
102711
Gefahrenklasse
8
Verpackungsgruppe
III
Harmonized Tariff Code
2933.99
TSCA
Yes
RTECS
HM3850000

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