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Homopiperazine is used to prepare 1,4-bis-(2-thiazolyl)-1,4-diazacycloheptane by reacting with 2-bromo-thiazole. It acts as an intermediate for repaglinide and fasudil hydrochloride. It is also used in the preparation of potent H3 receptor antagonists, which is used for the treatment of neurodegenerative conditions. Further, it is used in vesicant, cosmetic, emulsifier and energetic material. It acts as a corrosion inhibitor for iron. In pharmaceuticals, it is employed as antipyretic and reducing blood sugar, adiposity, calm, antipsychotic and anti-nervous.
Keypour, H.; Rezaeivala, M.; Mirzaei-Monsef, M.; Sayin, K.; Dilek, N.; Unver, H. Synthesis and characterization of Co(II), Ni(II), Cu(II) and Zn(II) complexes with a new homopiperazine macrocyclic Schiff base ligand. Inorg. Chim. Acta 2015, 432, 243-249.
Vinodh, R.; Bhagiyalakshmi, M.; Hemalatha, P.; Ganesh, M.; Peng, M. M.; Palanichamy, M.; Cha, W. S.; Jang, H. T. Homopiperazine Grafted Mesoporous Silicas from Rice Husk Ash for CO2 Adsorption. J. Nanosci. Nanotechnol. 2014, 14 (6), 4639-4648.
Gefahrenhinweise (EU): H303-H312-H314-H318
May be harmful if swallowed. Harmful in contact with skin. Causes severe skin burns and eye damage. Causes serious eye damage.
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.