I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.
It is an intermediate of medicine and agricultural chemicals. It is involved in the Suzuki-Miyaura cross-coupling reactions of heteroaryl compounds.
J. M. Bakke.; J. Riha. Preparation of 4-substituted 3-amino-2-chloropyridines, synthesis of a nevirapine analogue.Journal of Heterocyclic Chemistry. 2001, 38 (1),99-104 .
Takahiro Itoh.; Toshiaki Mase. Direct synthesis of hetero-biaryl compounds containing an unprotected NH2 group via Suzuki-Miyaura reaction. Tetrahedron Lett. 2005, 46 (20),3573-3577 .
Reaction with aroyl halides, followed by cyclization with PPSE (see Hexamethyldisiloxane, A11848), gives oxazolo[5,4-b]pyridines in high yield: Synthesis, 64 (1990):
Gefahrenhinweise (EU): H312-H315-H319-H335
Harmful in contact with skin. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Wear protective gloves/clothing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.