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Chloroacetyl chloride is an intermediate in the production of alachlor and butachlor. It is used to prepare phenacyl chloride through Friedel-Crafts acylation of benzene.
Huynh, T.; Valant, C.; Crosby, I. T.; Sexton, P. M.; Christopoulos, A.; Capuano, B. Synthesis and Pharmacological Evaluation of M4 Muscarinic Receptor Positive Allosteric Modulators Derived from VU10004. ACS Chem. Neurosci. 2015, 6 (6), 838-844.
Kuir, D.; Guillemineau, M.; Auzanneau, F. Aggregation of a Tetrasaccharide Acceptor Observed by NMR: Synthesis of Pentasaccharide Fragments of the LeaLex Tumor-Associated Hexasaccharide Antigen. J. Org. Chem. 2015, 80 (10), 5004-5013.
Gefahrenhinweise (EU): H301-H311-H331-H314-H372
Toxic if swallowed. Toxic in contact with skin. Toxic if inhaled. Causes severe skin burns and eye damage. Causes damage to organs through prolonged or repeated exposure.
Do not breathe dusts or mists. IF SWALLOWED: Immediately call a POISON CENTER/doctor IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.