A15970 Nicotinamide, 99%
SDS
| Größe | Preis ($) | Menge | Verfügbarkeit |
|---|---|---|---|
| 100g | 17,00 |
|
|
| 250g | 25,90 |
|
|
| 1000g | 79,70 |
|
|
Nicotinamide, 99%
Chemische Eigenschaften
Anwendungen
Nicotinamide is a building block (active component) of coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phopshate (NADP). It may be used as a substrate of nicotinamide phosphoribosyltransferase (NAMPT, EC 2.4.2.12), the rate-limiting enzyme for NAD(+) biosynthesis and an important signaling molecule. It is an amide derivative of vitamin B3 and a PARP inhibitor.
Bemerkungen
Literaturverweise
Kevin J.Bitterman; Rozalyn M.Anderson; Haim Y.Cohen; Magda Latorre-Esteves; David A.Sinclair. Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of Yeast Sir2 and Human SIRT1. The Journal of Biological Chemistry. 2002, 277, (47),45099-45107
Rozalyn M.Anderson; Kevin J.Bitterman; Jason G.Wood; Oliver Medvedik; David A.Sinclair. Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae. Letters to Nature. 2003, 423, 181-185
GHS Gefahren- und Sicherheitshinweise
Gefahrenhinweise (EU): H319
Causes serious eye irritation.
Sicherheitshinweise: P280i-P264-P305+P351+P338-P337+P313
Wear eye/face protection. Wash thoroughly after handling. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
