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It effectively promotes the proton conduction in polymer electrolyte membranes via an intermolecular proton-transfer mechanism. A useful triazole for proteomics research
Zhen Zhou.; Siwen Li.; Yuelan Zhang.; Meilin Liu.; Wen Li. Promotion of proton conduction in polymer electrolyte membranes by 1H-1,2,3-triazole.J Am Chem Soc.,2005,127(31), 10824-10825.
Kadir Dabak.; Özkan Sezer.; Ahmet Akar.; Olcay Anaç. Synthesis and investigation of tuberculosis inhibition activities of some 1,2,3-triazole derivatives.European Journal of Medicinal Chemistry,2003,38,(2), 215-218.
In weakly alkaline (bicarbonate) solution, this and other azoles promote the Baylis Hillman reaction (see 1,4-Diazabicyclo[2.2.2]octane, A14003), giving high yields with short reaction times: Tetrahedron Lett., 45, 5171 (2006).
Gefahrenhinweise (EU): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.