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86-84-0 - 1-Naphthyl isocyanate, 98% - A17200 - Alfa Aesar

A17200 1-Naphthyl isocyanate, 98%

CAS-Nummer
86-84-0
Synonyme

Größe Preis ($) Menge Verfügbarkeit
5g 40,17
25g 147,60
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1-Naphthyl isocyanate, 98%

MDL
MFCD00003881
EINECS
201-703-7

Chemische Eigenschaften

Formel
C11H7NO
Molmasse
169.18
Schmelzpunkt
Siedepunkt
269°
Flammpunkt
135°(275°F)
Dichte
1.177
Brechungsindex
1.6335
Sensitivität
Moisture Sensitive
Löslichkeit
Miscible with alcohol, chloroform and diethyl ether.

Anwendungen

1-Naphthyl isocyanate is used in the preparation of cationic aromatic urethane. It is useful for the study of cholangiolitic hepatotoxicity in laboratory animals. It is also employed as separate enantiomers of beta-blockers.

Bemerkungen

Moisture and light sensitive. Incompatible with strong oxidizing agents and alcohols.

Literaturverweise

Belal, F.; Walash, M.; El-Enany, N.; Zayed, S. Highly sensitive HPLC method for assay of aliskiren in human plasma through derivatization with 1-naphthyl isocyanate using UV detection. J. Chromatogr. B 2013, 933, 24-29.

McEntyre, C. J.; Slow, S.; Lever, M. Measurement of plasma free choline by high performance liquid chromatography with fluorescence detection following derivatization with 1-naphthyl isocyanate. Anal. Chim. Acta 2009, 644 (1-2), 90-94.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H331-H315-H319-H335-H334

Toxic if inhaled. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. May cause allergy or asthma symptoms or breathing difficulties if inhaled.

Sicherheitshinweise: P260-P280h-P305+P351+P338-P309-P310

Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/clothing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or if you feel unwell: Immediately call a POISON CENTER or doctor/physician.

Weitere Referenzen

Merck
14,6410
Beilstein
742779
Gefahrenklasse
6.1
Verpackungsgruppe
III
Harmonized Tariff Code
2929.10
TSCA
Yes

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