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It is employed as a specialty solvent. It is a solvent for active ingredients especially DHA for sunless tanning products. It is also utilized as viscosity controlling agent.
Hossein Zia.; Joseph K. H. Ma.; John P. O'Donnell. ; Louis A. Luzzi. Cosolvency of Dimethyl Isosorbide for Steroid Solubility.Pharm. Res. 1991, 8 (4),502-504.
Morgan Durand.; Adrien Mouret.; Valérie Molinier.; Thierry Féron.; Jean-Marie Aubry. Bitumen fluxing properties of a new class of sustainable solvents: The isosorbide di-alkyl ethers. Fuel. 2010, 89 (10),2729-2734.