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Murexide is used as a complexometric indicator in analytical chemistry for complexometric titrations of calcium, copper nickel and cobalt. It is an inhibitor of dihydrofolate reductase. Further, it acts as an enhancer of sonochemical destruction of chlorinated hydrocarbon pollutants.
Yi, X.; Bernot, K.; Le Corre, V.; Calvez, G.; Pointillart, F.; Cador, O.; Le Guennic, B.; Jung, J.; Maury, O.; Placide, V. Unraveling the Crystal Structure of Lanthanide-Murexide Complexes: Use of an Ancient Complexometry Indicator as a Near-Infrared-Emitting Single-Ion Magnet. Chem. Eur. J. 2014, 20 (6), 1569-1576.
Li, R.; He, Q.; Hu, Z.; Zhang, S.; Zhang, L.; Chang, X. Highly selective solid-phase extraction of trace Pd(II) by murexide functionalized halloysite nanotubes. Anal. Chim. Acta 2012, 713, 136-144.