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2-Bromo-5-(trifluoromethyl)aniline is used in the synthesis and biochemical evaluation of series of inhibitors of hepatitis C virus (HCV) NS3 protease.
Robert Rönn.; Anna Lampa.; Shane D. Peterson.; Thomas Gossas.; Eva Åkerblom.; U. Helena Danielson.; Anders Karlén.; Anja Sandström. Hepatitis C virus NS3 protease inhibitors comprising a novel aromatic P1moiety.Bioorg Med Chem.,
Tomoki Takeuchi.; Shinya Oishi.; Toshiaki Watanabe.; Hiroaki Ohno.; Jun-ichi Sawada.; Kenji Matsuno.; Akira Asai.; Naoya Asada.; Kazuo Kitaura.; and Nobutaka Fujii. Structure-Activity Relationships of Carboline and Carbazole Derivatives as a Novel Class of ATP-Competitive Kinesin Spindle Protein Inhibitors.J. Med. Chem.,2011,54(13), 4839-4846.
Gefahrenhinweise (EU): H302-H311-H332-H315-H319
Harmful if swallowed. Toxic in contact with skin. Harmful if inhaled. Causes skin irritation. Causes serious eye irritation.
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/clothing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.