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454-79-5 - 2-Bromo-5-(trifluoromethyl)aniline, 97% - 3-Amino-4-bromobenzotrifluoride - A17810 - Alfa Aesar

A17810 2-Bromo-5-(trifluoromethyl)aniline, 97%

CAS-Nummer
454-79-5
Synonyme
3-Amino-4-bromobenzotrifluoride

Größe Preis ($) Menge Verfügbarkeit
1g 18,09
5g 54,32
25g 275,40
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2-Bromo-5-(trifluoromethyl)aniline, 97%

MDL
MFCD00007637
EINECS
207-227-6

Chemische Eigenschaften

Formel
C7H5BrF3N
Molmasse
240.03
Siedepunkt
81-82°/5mm
Flammpunkt
>110°(230°F)
Dichte
1.675
Brechungsindex
1.5220
Löslichkeit
Not miscible or difficult to mix in water.

Anwendungen

2-Bromo-5-(trifluoromethyl)aniline is used in the synthesis and biochemical evaluation of series of inhibitors of hepatitis C virus (HCV) NS3 protease.

Bemerkungen

Store away from oxidizing agents. Keep the container tightly closed in a cool, dry and well ventilated place.

Literaturverweise

Robert Rönn.; Anna Lampa.; Shane D. Peterson.; Thomas Gossas.; Eva Åkerblom.; U. Helena Danielson.; Anders Karlén.; Anja Sandström. Hepatitis C virus NS3 protease inhibitors comprising a novel aromatic P1moiety.Bioorg Med Chem.,2008,16(6), 2955-2967.

Tomoki Takeuchi.; Shinya Oishi.; Toshiaki Watanabe.; Hiroaki Ohno.; Jun-ichi Sawada.; Kenji Matsuno.; Akira Asai.; Naoya Asada.; Kazuo Kitaura.; and Nobutaka Fujii. Structure-Activity Relationships of Carboline and Carbazole Derivatives as a Novel Class of ATP-Competitive Kinesin Spindle Protein Inhibitors.J. Med. Chem.,2011,54(13), 4839-4846.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H311-H302-H332-H315-H319

Toxic in contact with skin. Harmful if swallowed. Harmful if inhaled. Causes skin irritation. Causes serious eye irritation.

Sicherheitshinweise: P280h-P305+P351+P338-P309-P310-P302+P352

Wear protective gloves/clothing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or if you feel unwell: Immediately call a POISON CENTER or doctor/physician. IF ON SKIN: Wash with plenty of soap and water.

Weitere Referenzen

Beilstein
2094535
Gefahrenklasse
6.1
Verpackungsgruppe
III
Harmonized Tariff Code
2921.43
TSCA
No

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