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111-30-8 - Glutaraldehyde, 25% aq. soln. - Glutaric dialdehyde - Pentanedial - A17876 - Alfa Aesar

A17876 Glutaraldehyde, 25% aq. soln.

CAS-Nummer
111-30-8
Synonyme
Glutaric dialdehyde
Pentanedial

Größe Preis ($) Menge Verfügbarkeit
100ml 19,20
500ml 38,50
2500ml 94,70
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Glutaraldehyde, 25% aq. soln.

MDL
MFCD00007025
EINECS
203-856-5

Chemische Eigenschaften

Formel
C5H8O2
Molmasse
100.12
Dichte
1.062
Brechungsindex
1.3730
Löslichkeit
Miscible with water, ethanol, benzene, ether, acetone, dichloromethane, ethylacetate, isopropanol, n-hexane and toluene.

Anwendungen

Glutaraldehyde is used for cross-linking proteins and polyhydroxy materials. Also used as a fixative for tissues and as an amine-reactive homobifunctional crosslinker. It is also used in coupling reaction of biotin hydrazides to nucleic acids which is useful for conjugating fluorescent hydrazides and hydroxylamines to DNA and for stabilization ofproteins on agarose beads,activation of polystyrene and glass, for immobilization of antibodies and antigens.

Bemerkungen

Heat and air sensitive. Incompatible with strong acids, strong bases and strong oxidizing agents.

Literaturverweise

For use in the Robinson synthesis of pseudopelletierine, see Acetone-1,3-dicarboxyl­ic acid, A13742.

Reaction with (R)-(-)-2-Phenyl­glycinol, A19030, gives an intermediate for asymmetric synthesis of alkaloids: Org. Synth. Coll., 9, 176 (1998).

Cho, K. L.; Hill, A. J.; Caruso, F.; Kentish, S. E. Chlorine Resistant Glutaraldehyde Crosslinked Polyelectrolyte Multilayer Membranes for Desalination. Adv. Mater. 2015, 27 (17), 2791-2796.

Vikram, A.; Bomberger, J. M.; Bibby, K. J. Efflux as a Glutaraldehyde Resistance Mechanism in Pseudomonas fluorescens and Pseudomonas aeruginosa Biofilms. Antimicrob. Agents Chemother. 2015, 59 (6), 3433-3440.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H302-H331-H314-H318-H334-H317

Harmful if swallowed. Toxic if inhaled. Causes severe skin burns and eye damage. Causes serious eye damage. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction.

Sicherheitshinweise: P260u-P284-P303+P361+P353-P305+P351+P338-P405-P501a

Wear respiratory protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,4472
Beilstein
605390
Gefahrenklasse
8
Verpackungsgruppe
III
Harmonized Tariff Code
2912.19
TSCA
Yes
RTECS
MA2450000

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