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68-41-7 - D-Cycloserine, 98+% - (R)-(+)-4-Amino-3-isoxazolidinone - A18000 - Alfa Aesar

A18000 D-Cycloserine, 98+%

CAS-Nummer
68-41-7
Synonyme
(R)-(+)-4-Amino-3-isoxazolidinone

Größe Preis ($) Menge Verfügbarkeit
1g 51,20
5g 197,00
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D-Cycloserine, 98+%

MDL
MFCD00005353
EINECS
200-688-4

Chemische Eigenschaften

Formel
C3H6N2O2
Molmasse
102.09
Schmelzpunkt
137° dec.
Sensitivität
Air Sensitive
Löslichkeit
Soluble in water. Slightly soluble in methanol and propylene glycol. Insoluble in chloroform and ether.

Anwendungen

Cycloserine is an amino acid analog antibiotic used for the treatment of tuberculosis and rarely used for the treatment of noninfectious diseases. It acts as a competitive inhibitor of D-alanine during peptidoglycan synthesis. It inhibits bacterial cell wall biosynthesis and prevents the conversion of D-Alanine to L-Alanine.

Bemerkungen

Air Sensitive. Store in cool place. Incompatible with strong oxidizing agents.

Literaturverweise

Philbert, J.; Beeske, S.; Belzung, C.; Griebel, G. The CRF1 receptor antagonist SSR125543 prevents stress-induced long-lasting sleep disturbances in a mouse model of PTSD: Comparison with paroxetine and d-cycloserine. Behav Brain Res 2015, 279, 41-46.

Hofmann, S. G.; Carpenter, J. K.; Otto, M. W.; Rosenfield, D.; Smits, J. A. J.; Pollack, M. H. Dose timing of d-cycloserine to augment cognitive behavioral therapy for social anxiety: Study design and rationale. Contemp. Clin. Trials 2015, 43, 223-230.

Weitere Referenzen

Merck
14,2751
Beilstein
80798
Harmonized Tariff Code
2941.90
TSCA
No
RTECS
NY2975000

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