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613-93-4 - N-Methylbenzamide, 99% - A18057 - Alfa Aesar

A18057 N-Methylbenzamide, 99%

CAS-Nummer
613-93-4
Synonyme

Größe Preis ($) Menge Verfügbarkeit
5g 50,88
25g 161,87
100g 548,72
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N-Methylbenzamide, 99%

MDL
MFCD00011642
EINECS
210-362-3

Chemische Eigenschaften

Formel
C8H9NO
Molmasse
135.17
Schmelzpunkt
76-81°
Löslichkeit
Insoluble in water.

Anwendungen

It acts as a potent PDE10A (phosphodiesterase with a remarkable localization as the protein is abundant only in brain tissue) inhibitor. It is also employed as a pharmaceutical intermediate.

Bemerkungen

Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literaturverweise

John Paul Kilburn.; Jan Kehler.; Morten Langgård.; Mette N. Erichsen.; Sebastian Leth-Petersen.; Mogens Larsen.; Claus Tornby Christoffersen.; Jacob Nielsen. N-Methylanilide and N-methylbenzamide derivatives as phosphodiesterase 10A (PDE10A) inhibitors.Bioorg Med Chem.,2010,21(19), 6053-6062.

Walter H. Puterbaugh.; Charles R. Metalation of N-Methylbenzamide with Excess n-Butyllithium. Condensations with Electrophilic Compounds to Form ortho Derivatives. Cyclizations.J. Org. Chem.,1964,29(4), 853-856.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280-P305+P351+P338-P304+P340-P362-P301+P312-P312-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Harmonized Tariff Code
2924.29
TSCA
Yes
RTECS
CV5570000

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