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7554-65-6 - 4-Methyl-1H-pyrazole, 97+% - Fomepizole - A18083 - Alfa Aesar

A18083 4-Methyl-1H-pyrazole, 97+%

CAS-Nummer
7554-65-6
Synonyme
Fomepizole

Größe Preis ($) Menge Verfügbarkeit
1g 68,60
5g 226,40
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4-Methyl-1H-pyrazole, 97+%

MDL
MFCD00005245
EINECS
231-445-0

Chemische Eigenschaften

Formel
C4H6N2
Molmasse
82.11
Schmelzpunkt
13°
Siedepunkt
204-207°
Flammpunkt
96°(204°F)
Dichte
1.018
Brechungsindex
1.4945
Sensitivität
Hygroscopic
Löslichkeit
Miscible with water, ether, benzene and alcohol.

Anwendungen

4-Methyl-1H-pyrazole is used as an antidote in methanol and ethylene glycol poisoning. It is also employed as an alcohol dehydrogenase inhibitor. It acts a ligand in coordination chemistry. Further, it serves as an intermediate in organic synthesis.

Bemerkungen

Hygroscopic. Incompatible withstrong oxidizing agents, strong acids, acid chlorides, acid anhydrides and chloroformates.

Literaturverweise

Vlaicu, I. D.; Olar, R.; Marinescu, D.; Lazar, V.; Badea, M. Physico-chemical and thermal characterisation of new Co(II) complexes with pyrazole derivatives. J. Therm. Anal. Calorim. 2013, 113 (3), 1337-1343.

Boji?, M.; Sedgeman, C. A.; Nagy, L. D.; Guengerich, F. P. Aromatic hydroxylation of salicylic acid and aspirin by human cytochromes P450. Eur. J. Pharm. Sci. 2015, 73, 49-56.

Finnerty, N.; O'Riordan, S. L.; Klamer, D.; Lowry, J.; Pålsson, E. Increased brain nitric oxide levels following ethanol administration. Nitric Oxide 2015, 47, 52-57.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280-P305+P351+P338-P304+P340-P362-P301+P312-P312-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,4216
Beilstein
105204
Harmonized Tariff Code
2933.19
TSCA
No
RTECS
UQ7350000

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