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1821-12-1 - 4-Phenylbutyric acid, 99% - A18115 - Alfa Aesar

A18115 4-Phenylbutyric acid, 99%

CAS-Nummer
1821-12-1
Synonyme

Größe Preis ($) Menge Verfügbarkeit
25g 46,89
100g 148,50
500g 540,00
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4-Phenylbutyric acid, 99%

MDL
MFCD00004403
EINECS
217-341-8

Chemische Eigenschaften

Formel
C6H5(CH2)3CO2H
Molmasse
164.20
Schmelzpunkt
49-53°
Siedepunkt
165°/10mm
Flammpunkt
>110°(230°F)
Löslichkeit
Soluble in water and methanol.

Anwendungen

4-Phenylbutyric acid is used as a chemical chaperone involved in protein-folding disorders. It is involved in the synthesis of dyes and an active pharmaceutical ingredient intermediate.

Bemerkungen

Styrene-DVB; Strongly basic gel type resin.Incompatible with strong oxidizing agents.

Literaturverweise

Kolb, P. S.; Ayaub, E. A.; Zhou, W.; Yum, V.; Dickhout, J. G.; Ask, K. The therapeutic effects of 4-phenylbutyric acid in maintaining proteostasis. Int. J. Biochem. Cell Biol. 2015, 61, 45-52.

Hachuła, B.; Jabłońska-Czapla, M.; Flakus, H. T.; Nowak, M.; Kusz, J. H/D isotopic recognition and temperature effects in IR spectra of hydrogen-bonded cyclic dimers in crystals: 3-Methylcinnamic acid and 4-phenylbutyric acid. Spectrochim. Acta, Part A 2015, 134, 592-597.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Beilstein
638180
Harmonized Tariff Code
2916.39
TSCA
Yes

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