Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

996-50-9 - N-(Trimethylsilyl)diethylamine, 98% - (Diethylamino)trimethylsilane - TMSDEA - A18149 - Alfa Aesar

A18149 N-(Trimethylsilyl)diethylamine, 98%

CAS-Nummer
996-50-9
Synonyme
(Diethylamino)trimethylsilane
TMSDEA

Größe Preis ($) Menge Verfügbarkeit
25g 44,50
100g 135,00
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

N-(Trimethylsilyl)diethylamine, 98%

MDL
MFCD00009040
EINECS
213-637-6

Chemische Eigenschaften

Formel
(CH3)3SiN(CH2CH3)2
Molmasse
145.32
Schmelzpunkt
-10°
Siedepunkt
125-126°
Flammpunkt
10°(50°F)
Dichte
0.760
Brechungsindex
1.4110
Sensitivität
Moisture Sensitive
Löslichkeit
Hydrolyzes in water.

Anwendungen

It is used to derivative polar organic compounds. N,N-Diethyl(trimethylsilyl)amine is a chemical reagent with wide application in organic chemistry and used in stereo specific addition reactions as well as in SN2 nucleophilic substitutions.

Bemerkungen

Moisture Sensitive. Store away from oxidizing agents, water/moisture. Store under inert gas. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literaturverweise

Said Kinani.; Stéphane Bouchonnet.; Sophie Bourcier.; Jean-Marc Porcher.; Sélim Aït-Aïssa.Study of the chemical derivatization of zearalenone and its metabolites for gas chromatography-mass spectrometry analysis of environmental samples.J Chromatogr A.2008,1190(1), 307-315.

Yasushi Yamamoto.; Hideaki Shimizu.; Chinami Matui.; & Michiru Chind. Transformation of Oxiranes to β-Trimethylsilyloxyalkyl Iodide by N-(Trimethylsilyl) diethylamine and Methyl Iodide.Main Group Chem.1996,1(4), 409-414.

Moderately powerful silylating agent which functions as its own base (see Appendix 4). In the silylation of alcohols, the reagent is sensitive to steric effects. Thus, the equatorial hydroxyl group of 3-ß-tropanol can be silylated selectively: Acta Chim. Acad. Sci. Hung., 58, 189 (1968); J. Am. Chem. Soc., 96, 5876 (1974).

In the presence of MeI, primary amines such as aniline are converted to their N,N-bis(trimethylsilyl) derivatives: J. Organomet. Chem., 510, 1 (1996), and ketones to silyl enol ethers in high yield: Organometallics, 16, 2204 (1997). The combination with an alkyl iodide or bromide also provides a convenient method for generating the iodo- or bromotrialkylsilane equivalent in ring-opening of cyclic ethers. With 1 mol of reagent the main product is the ω-siloxy alkyl halide; excess reagent affords the terminal dihalide: J. Org. Chem., 64, 8024 (1999).

Promotes direct 1,4-addition of ɑ-unsubstituted aldehydes to electron deficient olefins, specifically with enones to give δ-keto aldehydes: J. Chem. Soc., Perkin 1, 316 (2001). Alternative conditions were found to be ineffective.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H225-H314-H318

Highly flammable liquid and vapour. Causes severe skin burns and eye damage. Causes serious eye damage.

Sicherheitshinweise: P210-P260u-P303+P361+P353-P305+P351+P338-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Do not breathe dusts or mists. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Beilstein
635718
Gefahrenklasse
3
Verpackungsgruppe
II
Harmonized Tariff Code
2931.90
TSCA
Yes

Empfohlen

  • A16089

    3-Methyl-2-buten-1-ol, 98+%
  • L02809

    Tetra-n-butylammonium hydroxide, 40% w/w aq. soln.
  • L18489

    Aluminum chloride, anhydrous, powder, 99%

Kürzlich angesehen

Chemikalien

Life science

Metalle und Stoffe

Katalysatoren

Forschungs- und Laborbedarf