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206658-89-1 - 3-Aminobenzeneboronic acid monohydrate, 97% - 3-Aminophenylboronic acid monohydrate - A18189 - Alfa Aesar

A18189 3-Aminobenzeneboronic acid monohydrate, 97%

CAS-Nummer
206658-89-1
Synonyme
3-Aminophenylboronic acid monohydrate

Größe Preis ($) Menge Verfügbarkeit
1g 55,11
5g 197,76
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3-Aminobenzeneboronic acid monohydrate, 97%

MDL
MFCD00149554
EINECS
250-189-0

Chemische Eigenschaften

Formel
C6H8BNO2•H2O
Molmasse
154.96 (136.95anhy)
Schmelzpunkt
93-97°
Sensitivität
Air & Moisture Sensitive
Löslichkeit
Soluble in DMSO and methanol.

Anwendungen

It is employed as a reagent in the preparation of Suzuki-Miyaura cross-coupling, used for Gram-positive ant virulence drugs and inhibitors of Streptococcus agalactiae Stk1, regioisomer of Zaleplon (a sedative), amphiphilic random glycopolymer, which self-assemble to form nanoparticles, with potential as a glucose-sensitive matrix, chemomechanical polymer that expands and contracts in blood plasma with high glucose selectivity. Aminophenylboronic Acid is also used as a reagent in the preparation of nonbenzodiazepine hypnotic agents.

Bemerkungen

Air & Moisture Sensitive. Store away from oxidizing agents, air, water/moisture. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literaturverweise

Gregory D. Cuny.; Maxime Robin.; Natalia P. Ulyanova.; Debasis Patnaik.; Valerie Pique.; Gilles Casano.; Ji-Feng Liu.; Xiangjie Lin.; Jun Xian.; Marcie A. Glicksman.; Ross L. Stein.; Jonathan M.G. Higgins. Structure-activity relationship study of acridine analogs as haspin and DYRK2 kinase inhibitors.Bioorg Med Chem Lett.2010,20(12), 3491-3494.

Xingju Jin.; Xinge Zhang.; Zhongming Wu.; Dayong Teng.; Xuejiao Zhang.; Yanxia Wang.; Zhen Wang.; Chaoxing Li. Amphiphilic random glycopolymer based on phenylboronic acid: synthesis, characterization, and potential as glucose-sensitive matrix.Biomacromolecules.2009,10(6), 1337-1345.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319

Causes skin irritation. Causes serious eye irritation.

Sicherheitshinweise: P280-P264-P305+P351+P338-P362-P321-P332+P313-P337+P313-P302+P352

Wear protective gloves/protective clothing/eye protection/face protection. Wash thoroughly after handling. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Take off contaminated clothing and wash before reuse. Specific treatment (see label). If skin irritation occurs: Get medical advice/attention. If eye irritation persists: IF ON SKIN: Wash with plenty of soap and water.

Weitere Referenzen

Beilstein
2936342
Harmonized Tariff Code
2931.90
TSCA
No

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