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42348-86-7 - 5-Chloro-1-indanone, 99% - A18308 - Alfa Aesar

A18308 5-Chloro-1-indanone, 99%

CAS-Nummer
42348-86-7
Synonyme

Größe Preis ($) Menge Verfügbarkeit
1g 46,50
5g 154,00
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5-Chloro-1-indanone, 99%

MDL
MFCD00041456

Chemische Eigenschaften

Formel
C9H7ClO
Molmasse
166.61
Schmelzpunkt
92-96°
Siedepunkt
124-125°/3mm
Löslichkeit
Insoluble in water.

Anwendungen

5-Chloro-1-indanone may be used as starting reagent for the preparation of 5-chloro-2-methoxycarbonyl-1-indanone. It may also be used for the preparation of important biomedical compounds such as anticonvulsants, anticholinergics and diarylsulfonylureas, having potential activity against solid tumors. It participates in the Irie?s synthesis of substituted pyridines.

Bemerkungen

Stable under recommended storage conditions. Incompatible with oxidizing agents.

Literaturverweise

Mark T. DuPriest; Charles L.Schmidt; Daniel Kuzmich; Stanly B.Williams. A facile synthesis of 7-halo-5H-indeno[1,2-b]pyridines and -pyridin-5-ones. J. Org. Chem. 1986, 51,(11), 2021-2023.

 

Tomas Pena Ruiz; Manuel Fernandez Gomez; Juan Jesus Lopez Gonzalez; Anna E.Koziol. Weak hydrogen-, halogen- and stacking π?π bonding in crystalline 5-chloro-1-indanone. An analysis by using X-ray diffraction, vibrational spectroscopy and theoretical methods. Chemical Physics. 2006, 320,(2-3), 164-180.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Beilstein
1448000
Harmonized Tariff Code
2914.70
TSCA
Yes

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