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5-Bromouridine is often incorporated into RNA in order to detect immunocytochemically and analyzed by cytometry. It possesses anti-viral activity and inhibits the activity of viruses such as human immunodeficiency virus.
Jonatha M. Gott.; Michael C. Willis.; Tad H. Koch.; Olke C. Uhlenbeck. A specific, UV-induced RNA-protein crosslink using 5-bromouridine-substituted RNA. Biochemistry. 1991, 30 (25), 6290-6295.
Paul O. P. Ts'o.; Sunney I. Chan. Interaction and Association of Bases and Nucleosides in Aqueous Solutions. II. Association of 6-Methylpurine and 5-Bromouridine and Treatment of Multiple Equilibria. J. Am. Chem. Soc. 1964, 86 (19), 4176-4181.