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3-Cyclohexyl-1-propyne, is used as a pharmaceutical intermediate. It can be used to produce (5-bromo-4,4,5,5-tetrafluoro-pent-2-enyl)-cyclohexane at the temperature of 40°C. It will need reagents (NH4)2S2O8, HCO2Na·2H2O and solvent dimethylformamide with the reaction time of 3 hours. It is also used as organic synthesis intermediates.
PH Lee.; S Kim.; A Park.; BC Chary. Gold (I)-Catalyzed Addition of Diphenyl Phosphate to Alkynes: Isomerization of Kinetic Enol Phosphates to the Thermodynamically Favored Isomers. Angewandte Chemie.2010122 (38), 6958-6961.
F Taherirastgar.; L Brandsma. Conversion of Alkyl-and Arylallenes into 1-Alkynes Through Metallated Intermediates. Synthetic communications.199727 (23), 4035-4040.
Gefahrenhinweise (EU): H226
Flammable liquid and vapour.
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Wear protective gloves and eye/face protection. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. Dispose of contents/container in accordance with local/regional/national/international regulations.