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56-75-7 - (R,R)-Chloramphenicol, 99+% - Chloromycetin - B20841 - Alfa Aesar

B20841 (R,R)-Chloramphenicol, 99+%

CAS-Nummer
56-75-7
Synonyme
Chloromycetin

Größe Preis ($) Menge Verfügbarkeit
25g 46,40
100g 137,00
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(R,R)-Chloramphenicol, 99+%

MDL
MFCD00078159
EINECS
200-287-4

Chemische Eigenschaften

Formel
C11H12Cl2N2O5
Molmasse
323.14
Schmelzpunkt
149-152°
Löslichkeit
Soluble in alcohol, propylene, glycol, acetone and ethyl acetate. Slightly soluble in water.

Anwendungen

Inhibitor of translation on the 50S subunit at the peptidyltransferase step. (R,R)-Chloramphenicol is widely utilized as an antibiotic, which is used for the treatment of number of bacterial infections and also act as a bacteriostatic. It is often used for bacterial selection in molecular biology applications. It also finds an application in ophthalmic and veterinary purposes. It also protects the mitochondrial and chloroplast protein synthesis and ribosomal formation of (p)ppGpp, de-pressing rRNA transcription.

Bemerkungen

Keep the container tightly sealed. Incompatible with strong oxidizing agents.

Literaturverweise

Fedeniuk, R. W.; Mizuno, M.; Neiser, C.; O’Byrne, C. Development of LC-MS/MS methodology for the detection/determination and confirmation of chloramphenicol, chloramphenicol 3-O- β-d-glucuronide, florfenicol, florfenicol amine and thiamphenicol residues in bovine, equine and porcine liver. J. Chromatogr. B 2015, 991, 68-78.

Mitchell, S. M.; Ullman, J. L.; Teel, A. L.; Watts, R. J. Hydrolysis of amphenicol and macrolide antibiotics: Chloramphenicol, florfenicol, spiramycin, and tylosin. Chemosphere 2015, 134, 504-511.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H303-H350-H361

May be harmful if swallowed. May cause cancer. Suspected of damaging fertility or the unborn child.

Sicherheitshinweise: P201-P280-P312a-P308+P313-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. Call a POISON CENTER/doctor if you feel unwell. IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,2077
Beilstein
2225532
Harmonized Tariff Code
2941.40
TSCA
Yes
RTECS
AB6825000

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