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It is employed as a dopamine D1 receptor antagonist and a D1DR and D2DR inhibitor. Fluphenazine Dihydrochloride has been used to deliver Fluphenazine to biological systems in studies probing the effects and metabolic fates of this commonly used dopamine antagonist. It is also employed as an antipsychotic.
G Cai, et al. Inverse agonist properties of dopaminergic antagonists at the D(1A) dopamine receptor: uncoupling of the D(1A) dopamine receptor from G(s) protein.Mol Pharmacol.199956(5), 989-996.
Trzeciak HI, et al. Behavioral effects of withdrawal of fluphenazine after long-term treatment. Arzneimittelforschung.1976,26(9), 1697-700.
Gefahrenhinweise (EU): H302
Harmful if swallowed.
Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Rinse mouth. Dispose of contents/container in accordance with local/regional/national/international regulations.