Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

119-65-3 - Isoquinoline, 97% - B21279 - Alfa Aesar

B21279 Isoquinoline, 97%

CAS-Nummer
119-65-3
Synonyme

Größe Preis ($) Menge Verfügbarkeit
100g 58,10
500g 186,00
2500g 591,00
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

Isoquinoline, 97%

MDL
MFCD00006898
EINECS
204-341-8

Chemische Eigenschaften

Formel
C9H7N
Molmasse
129.16
Schmelzpunkt
24-27°
Siedepunkt
241-243°
Flammpunkt
107°(225°F)
Dichte
1.090
Brechungsindex
1.6245
Löslichkeit
Soluble in water (5g/L).

Anwendungen

Isoquinoline is used in the manufacture of dyes, paints, antifungal. It is also used as a solvent for the extraction of resins and terpenes.

Bemerkungen

Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Literaturverweise

Maria Chrzanowska.; Maria D. Rozwadowska. Asymmetric Synthesis of Isoquinoline Alkaloids. Chem. Rev. 2004, 104, (7), 3341-3370.

Ryoji. Noyori.; Masako. Ohta.; Yi. Hsiao.; Masato. Kitamura.; Tetsuo. Ohta.; Hidemasa. Takaya. Asymmetric synthesis of isoquinoline alkaloids by homogeneous catalysis. J. Am. Chem. Soc. 1986, 108, (22), 7117-7119.

Reacts with various acid halides in the presence of CN- to give "Reissert compounds" (1-cyano-2-acyl 1,2-dihydro derivatives). For reviews, see: Chem. Rev., 55, 511 (1955); Adv. Het. Chem., 9, 1 (1968); 24, 187 (1979). 1-Alkylisoquinolines can be prepared by alkylation of the Li or Na derivatives of Reissert compounds: Org. Synth. Coll., 4, 641 (1963); 6, 115 (1988). For formation of Reissert compounds from a variety of carbonyl, sulfonyl and phosphoryl halides under milder, phase-transfer conditions, see: Synthesis, 497 (1977). For 'direct' cyanation by a modified Reissert procedure in the presence of tosyl chloride followed by DBU, see: J. Org. Chem., 49, 4056 (1984).

A one-step synthesis of 1-nitroisoquinoline has been reported in which isoquinoline reacts with KNO2 in the presence of acetic anhydride and DMSO. The reaction is considered to be analogous to the Pfitzner-Moffatt oxidation (see Dimethyl­ sulfoxide, A13280): J. Chem. Soc., Perkin 1, 1777 (1996).

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H311-H302-H315-H319

Toxic in contact with skin. Harmful if swallowed. Causes skin irritation. Causes serious eye irritation.

Sicherheitshinweise: P280-P305+P351+P338-P361-P362-P301+P312-P312-P363-P321-P405-P501a

Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Remove/Take off immediately all contaminated clothing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Wash contaminated clothing before reuse. Specific treatment (see label). Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,5222
Beilstein
107549
Gefahrenklasse
6.1
Verpackungsgruppe
II
Harmonized Tariff Code
2933.49
TSCA
Yes
RTECS
NW6825000

Empfohlen

Kürzlich angesehen

Chemikalien

Life science

Metalle und Stoffe

Katalysatoren

Forschungs- und Laborbedarf