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2156-56-1 - Sodium dichloroacetate, 97% - Dichloroacetic acid sodium salt - B21827 - Alfa Aesar

B21827 Sodium dichloroacetate, 97%

CAS-Nummer
2156-56-1
Synonyme
Dichloroacetic acid sodium salt

Größe Preis ($) Menge Verfügbarkeit
10g 60,60
50g 230,00
250g 844,00
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Sodium dichloroacetate, 97%

MDL
MFCD00070489
EINECS
218-461-3

Chemische Eigenschaften

Formel
Cl2CHCO2Na
Molmasse
150.93
Schmelzpunkt
197-199° dec.
Sensitivität
Moisture Sensitive
Löslichkeit
Soluble in water.

Anwendungen

Sodium dichloroacetate finds medicinal application in removing warts and other skin growths. It is used as an antidote for lactic acidosis and in the treatment of stroke. It is studied as potential drugs, since it inhibits the enzyme pyruvate dehydrogenase kinase.

Bemerkungen

Moisture sensitive. Incompatible with strong oxidizing agents.

Literaturverweise

Agnoletto, C.; Brunelli, L.; Melloni, E.; Pastorelli, R.; Casciano, F.; Rimondi, E.; Rigolin, G. M.; Cuneo, A.; Secchiero, P.; Zauli, G. The anti-leukemic activity of sodium dichloroacetate in p53mutated/null cells is mediated by a p53-independent ILF3/p21 pathway. Oncotarget 2015, 6 (4), 2385-2396.

Ji, B.; Tang, P.; Yan, K.; Sun, G. Catalytic actions of alkaline salts in reactions between 1, 2, 3, 4-butanetetracarboxylic acid and cellulose: II. Esterification. Carbohydr. Polym. 2015, 132, 228-236.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H303-H315-H319-H341-H335

May be harmful if swallowed. Causes skin irritation. Causes serious eye irritation. Suspected of causing genetic defects. May cause respiratory irritation.

Sicherheitshinweise: P201-P261-P280-P305+P351+P338-P405-P501a

Obtain special instructions before use. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Harmonized Tariff Code
2915.40
TSCA
No

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