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656-65-5 - 4-Bromo-3-fluoroaniline, 98% - B22227 - Alfa Aesar

B22227 4-Bromo-3-fluoroaniline, 98%

CAS-Nummer
656-65-5
Synonyme

Größe Preis ($) Menge Verfügbarkeit
10g 161,20
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4-Bromo-3-fluoroaniline, 98%

MDL
MFCD00672933
EINECS
000-000-0

Chemische Eigenschaften

Formel
C6H5BrFN
Molmasse
190.01
Schmelzpunkt
65-70°
Flammpunkt
104°(219°F)
Löslichkeit
Soluble in acetonitrile, methanol. Insoluble in water.

Anwendungen

4-Bromo-3-fluoroaniline is an intermediate used for the synthetic preparation of Tradizolid and various pharmaceuticals such as the synthesis of several lateral difluoro-substituted 4,4"-dialkyl- and 4,4"-alkoxyalkylterphenyls.

Bemerkungen

Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

Literaturverweise

V. Q. Yen; N. P. Buu-hoi, N. D. Xuong. Fluorinated Isatins and Some of Their Heterocyclic Derivatives. J. Org. Chem. 1958, 23 (12), 1858-1861.

Makoto Ishikawa; Katsumasa Nonoshita; Yoshio Ogino; Yoshikazu Nagae; Daisuke Tsukahara; Hideka Hosaka; Hiroko Maruki; Sumika Ohyam; Riki Yoshimoto; Kaori Sasaki; Yasufumi Nagata; Jun-ichi Eiki; Teruyuki Nishimura. Discovery of novel 2-(pyridine-2-yl)-1H-benzimidazole derivatives as potent glucokinase activators. Bioorganic & Medicinal Chemistry Letters. 2009, 19 (15), 4450-4454.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H331-H302-H312-H315-H319-H335

Toxic if inhaled. Harmful if swallowed. Harmful in contact with skin. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280-P305+P351+P338-P304+P340-P311-P362-P301+P312-P312-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Call a POISON CENTER or doctor/physician. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Beilstein
3236457
Gefahrenklasse
6.1
Verpackungsgruppe
III
Harmonized Tariff Code
2921.42
TSCA
No

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