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Phenyl acetate levels in urine are marker for the diagnosis of some forms of unipolar major depressive disorders. It undergoes Fries rearrangement to form a mixture of o- and p-hydroxyacetophenones which are useful intermediates in manufacture of pharmaceuticals. It is a metabolite of Phenylbutyrate (PB), useful in the treatment of neuroblastoma and lung cancer. An odorant found in strawberries, passion fruit and black tea.
H.C.Sabelli; J.Fawcett; F.Gusovsky; J.Javaid; J.Edwards; H.Jeffriess. Urinary phenyl acetate: a diagnostic test for depression? Science. 1983, 220,(4602), 1187-1188.
F.Jayat; M.J.Sabater Picot; M.Guisnet. Solvent effects in liquid phase Fries rearrangement of phenyl acetate over a HBEA zeolite. Catalysis Letters. 1996, 41,(3), 181-187.
Gefahrenhinweise (EU): H227-H302
Combustible liquid. Harmful if swallowed.
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