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65-49-6 - 4-Aminosalicylic acid, 98+% - 4-Amino-2-hydroxybenzoic acid - B23289 - Alfa Aesar

B23289 4-Aminosalicylic acid, 98+%

CAS-Nummer
65-49-6
Synonyme
4-Amino-2-hydroxybenzoic acid

Größe Preis ($) Menge Verfügbarkeit
100g 25,00
500g 81,80
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4-Aminosalicylic acid, 98+%

MDL
MFCD00007789
EINECS
200-613-5

Chemische Eigenschaften

Formel
C7H7NO3
Molmasse
153.14
Schmelzpunkt
ca 135-145° dec.
Löslichkeit
Soluble in water (2 g/L) at 20°C, dilute sodium hydroxide, dilute nitric acid, ether (slightly), methanol, acetone, and ethanol. Virtually insoluble in benzene, chloroform, and carbon tetrachloride.

Anwendungen

Competitive pteridine synthetase inhibitor, has antibacterial capable of inhibiting the growth of Mycobacterium tuberculosis. It inhibits NF-κB and folic acid synthesis.

Bemerkungen

Store in cool, dry place in a well sealed container. Store away from oxidizing agents.

Literaturverweise

Pawel Grobelny; Arijit Mukherjeea and Gautam R. Desiraju. Drug-drug co-crystals: Temperature-dependent proton mobility in the molecular complex of isoniazid with 4-aminosalicylic acid. CrystEngComm. 2011, 13 (13), 4358-4364.

John Gandolfo; Louis A. Weiss; Michael Farthing, George Powers; Kathleen Eagen; Michael Goldberg; Phillip Berman; Marshall Kaplan. 4-Aminosalicylic acid retention enemas in treatment of distal colitis. Digestive Diseases and Sciences. 1987, 32 (7), 700-704.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,477
Beilstein
473071
Harmonized Tariff Code
2922.50
TSCA
Yes
RTECS
VO1225000

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