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2-Bromopropionyl chloride is a reagent that is used in the preparation of pyrazinecarboxamide-based inhibitors of diacylglycerol acyltransferase. It is also used in the synthesis of 2-aminopropionyl polystyrene resin by Friedel Crafts reaction.
Katja Jankova, et al. Synthesis of poly(styrene-b-isobutylene-b-styrene) triblock copolymer by ATRP.Polym. Bull.,1998,41(6), 639-644.
Su-Sun. Wang. Solid phase synthesis of protected peptides via photolytic cleavage of the .alpha.-methylphenacyl ester anchoring linkage.J. Org. Chem.,1976,41(20), 3258-3261.
Gefahrenhinweise (EU): H226-H314-H318
Flammable liquid and vapour. Causes severe skin burns and eye damage. Causes serious eye damage.
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Do not breathe dusts or mists. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.