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89-57-6 - 5-Aminosalicylic acid, 95% - 5-Amino-2-hydroxybenzoic acid - Mesalamine - B23970 - Alfa Aesar

B23970 5-Aminosalicylic acid, 95%

CAS-Nummer
89-57-6
Synonyme
5-Amino-2-hydroxybenzoic acid
Mesalamine

Größe Preis ($) Menge Verfügbarkeit
100g 50,47
500g 156,56
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5-Aminosalicylic acid, 95%

MDL
MFCD00007877
EINECS
201-919-1

Chemische Eigenschaften

Formel
C7H7NO3
Molmasse
153.14
Schmelzpunkt
ca 280° dec.
Löslichkeit
Soluble in dimethyl sulfoxide.

Anwendungen

5-Aminosalicylic acid is used in the preparation of gastrointestinal anti-inflammatory agents. It is a metabolite of sulfasalazine. It acts as a drug involved in the treatment of Crohn’s disease and ulcerative colitis. Further, it is used to make dyes and light-sensitive papers.

Bemerkungen

Moisture, air and light sensitive. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides and chloroformates.

Literaturverweise

Bijani, S.; Jain, V.; Padmanabhan, D.; Pandey, B.; Shah, A. Mixed Pd/C and Pt/C as efficient catalysts for deuteration of Mesalamine. Tetrahedron Lett. 2015, 56 (10), 1211-1214.

Goyanes, A.; Buanz, A. B. M.; Hatton, G. B.; Gaisford, S.; Basit, A. W. 3D printing of modified-release aminosalicylate (4-ASA and 5-ASA) tablets. Eur. J. Pharm. Biopharm. 2015, 89, 157-162.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,5904
Beilstein
2090421
Harmonized Tariff Code
2922.50
TSCA
Yes
RTECS
VO1400000

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