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1-Methyl-2-pyridone is used in pharmaceutical industry. A common problem with hydrophobic non-natural base pairsthe inefficient extension following such a base pairis reduced by using the methylpyridone scaffold, which simultaneously limits another frequent problem of non-natural bases: mispairs with deoxyadenosine.
J Shailaja, S Karthikeyan.; V Ramamurthy. Cyclodextrin mediated solvent-free enantioselective photocyclization of N-alkyl pyridones.Tetrahedron Lett. 2002, 43 (51),9335-9339 .
Gefahrenhinweise (EU): H302-H315-H319-H335
Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
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