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447-61-0 - 2-(Trifluoromethyl)benzaldehyde, 98% - alpha,alpha,alpha-Trifluoro-o-tolualdehyde - B24591 - Alfa Aesar

B24591 2-(Trifluoromethyl)benzaldehyde, 98%

CAS-Nummer
447-61-0
Synonyme
alpha,alpha,alpha-Trifluoro-o-tolualdehyde

Größe Preis ($) Menge Verfügbarkeit
5g 31,70
25g 61,40
100g 180,00
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2-(Trifluoromethyl)benzaldehyde, 98%

MDL
MFCD00003337
EINECS
207-185-9

Chemische Eigenschaften

Formel
C8H5F3O
Molmasse
174.12
Schmelzpunkt
-40°
Siedepunkt
70-71°/16mm
Flammpunkt
61°(141°F)
Dichte
1.322
Brechungsindex
1.4660
Sensitivität
Air Sensitive
Löslichkeit
Soluble in most organic solvents.

Anwendungen

2-(Trifluoromethyl)benzaldehyde has been used in the preparation of ω-(dimethylamino)-alkylethyl-4(-2-(trifluorormethyl)phenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylates, methyl (E)-2-[2-[(E)-2-(2-trifluoromethylphenyl)vinyl]-phenyl]-3-methoxyacrylate via Wittig-Horner reaction. It is a reagent used as electrophilic component in a wide array of reactions.

Bemerkungen

Air sensitive. Store under dry inert gas. Store away from oxidizing agents, air.

Literaturverweise

N Baindur; A Rutledge; D J Triggle. A homologous series of permanently charged 1,4-dihydropyridines: novel probes designed to localize drug binding sites on ion channels. Journal of Medicinal Chemistry. 1993, 36 (23), 3743-3745.

J Alzeer, J Chollet; I Heinze-Krauss; C Hubschwerlen; H Matile; R G Ridley. Phenyl beta-methoxyacrylates: a new antimalarial pharmacophore. Journal of Medicinal Chemistry. 2000, 43 (4), 560-568.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H302-H315-H319-H335-H227

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. Combustible liquid.

Sicherheitshinweise: P280g-P305+P351+P338

Wear protective gloves. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Weitere Referenzen

Beilstein
2045512
Harmonized Tariff Code
2913.00
TSCA
No

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