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6-Fluoroindole acts as a reagent in the synthesis of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles, which acts as a potential anticancer immunomodulator. It is also employed as an antifungal and antibacterial agent. Further, it serves as a potent selective serotonin reuptake inhibitor. In addition to this, it is used as a inhibitor of HIV-1 attachment.
Samanta, R.; Narayan, R.; Bauer, J. O.; Strohmann, C.; Sievers, S.; Antonchick, A. P. Oxidative regioselective amination of chromones exposes potent inhibitors of the hedgehog signaling pathway. Chem. Commun. 2015, 51 (5), 925-928.
Hayashi, R.; Ohmori, E.; Moriwaki, M.; Kumagai, H.; Isogaya, M. Indolylpiperidine derivatives as potent and selective alpha1B adrenoceptor antagonists. Bioorg. Med. Chem. Lett. 2015, 25 (18), 3921-3923.
Gefahrenhinweise (EU): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.