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389-08-2 - Nalidixic acid, 99% - 1,4-Dihydro-1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid - 1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid - B25096 - Alfa Aesar

B25096 Nalidixic acid, 99%

CAS-Nummer
389-08-2
Synonyme
1,4-Dihydro-1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid
1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid

Größe Preis ($) Menge Verfügbarkeit
5g 18,90
25g 67,14
100g 205,60
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

Nalidixic acid, 99%

MDL
MFCD00006884
EINECS
206-864-7

Chemische Eigenschaften

Formel
C12H12N2O3
Molmasse
232.24
Schmelzpunkt
228-230°
Löslichkeit
Soluble in diethyl ether, acetone, methylene chloride, chloroform and methanol. Insoluble in water.

Anwendungen

Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent. It is also used as an inhibitor of bacterial DNA gyrase. It plays an important role in the treatment of urinary tract infections caused by susceptible gram-negative microorganisms, including the majority of E. Coli, Enterobacter species, Klebsiella species and Proteus species.

Bemerkungen

Light sensitive and air sensitive. Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.

Literaturverweise

Chintagari, S.; Hung, Y. C.; Hamanaka, D. Resistance of various STEC strains and serogroups to UV radiation and effect of nalidixic acid adaptation. Food Control 2015, 50, 313-319.

Dwivedi, G. R.; Maurya, A.; Yadav, D. K.; Khan, F.; Darokar, M. P.; Srivastava, S. K. Drug Resistance Reversal Potential of Ursolic Acid Derivatives against Nalidixic Acid- and Multidrug-resistant Escherichia coli. Chem. Biol. Drug Des. 2015, 86 (3), 272-283.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H302

Harmful if swallowed.

Sicherheitshinweise: P264-P270-P301+P312-P330-P501a

Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,6359
Beilstein
750515
Harmonized Tariff Code
2933.99
TSCA
No
RTECS
QN2885000

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