2-Methyl-2-pyridylaminoethanol is used as a reagent to synthesize Rosiglitazone (Maleate: R693500), a thiazolinedione drug used to reduce insulin resistance in patients with Type 2 diabetes.
Tabassum Kirefu; Scott W Landvatter; Alison J Latter; Kenneth WM Lawrie; Donald J Morecombe and Kenneth Willcocks. Rosiglitazone maleate (BRL 49653-C); the preparation of [14C] and [3H] isotopomers. Journal of Labelled Compounds and Radiopharmaceuticals. 2001, 44 (5), 329-335.
Gefahrenhinweise (EU): H301-H315-H319-H335
Toxic if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF SWALLOWED: Immediately call a POISON CENTER/doctor IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.