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3680-69-1 - 6-Chloro-7-deazapurine, 98% - 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine - B25713 - Alfa Aesar

B25713 6-Chloro-7-deazapurine, 98%

CAS-Nummer
3680-69-1
Synonyme
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine

Größe Preis ($) Menge Verfügbarkeit
1g 274,00
5g 1077,00
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6-Chloro-7-deazapurine, 98%

MDL
MFCD01686865

Chemische Eigenschaften

Formel
C6H4ClN3
Molmasse
153.52
Schmelzpunkt
190-192°
Löslichkeit
Soluble in DMSO, ethyl acetate and methanol.

Anwendungen

6-Chloro-7-deazapurine is used for making tofacitinib.

Bemerkungen

Store in cool, dry place in a well sealed container. Store away from oxidizing agents.

Literaturverweise

Helmut Rosemeyer and Frank Seela. Stereoselective synthesis of pyrrolo[2,3-d]pyrimidine α- and β-D-ribonucleosides from anomerically pure D-ribofuranosyl chlorides: Solid-Liquid Phase-Transfer Glycosylation and 15N-NMR Spectra. Helvetica Chimica Acta. 1988, 71 (6), 1573-1585.

Balakumar Arumugham; Hyo-Joong Kim; Mark N. Prichard; Earl R. Kern; Chung K. Chu. Synthesis and antiviral activity of 7-deazaneplanocin A against orthopoxviruses (vaccinia and cowpox virus). Bioorganic & Medicinal Chemistry Letters. 2006, 16 (2), 285-287.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Harmonized Tariff Code
2933.59
TSCA
No

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