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4,4-Difluorocyclohexanone is used as a pharmaceutical intermediate.
Ruth E. Lack; Camille Ganter; John D. Roberts. Nuclear magnetic resonance spectroscopy. Conformational equilibria and equilibration of 4,4-difluorocyclohexanone and 6,6-difluoro-cis-decal-2-ones. J. Am. Chem. Soc. 1968, 90 (25), 7001-7007.
William R. Dolbier; Jorge H. Alonso. Secondary deuterium isotope effects in pericyclic reactions. Thermal rearrangement of dideuteriobiscyclopropylidene. J. Am. Chem. Soc. 1973, 95 (13), 4421-4423.
Gefahrenhinweise (EU): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Wear protective gloves. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.