Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

148893-10-1 - O-(7-Aza-1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate, 99% - HATU - 1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 1-oxide hexafluorophosphate - H26082 - Alfa Aesar

H26082 O-(7-Aza-1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate, 99%

CAS-Nummer
148893-10-1
Synonyme
HATU
1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 1-oxide hexafluorophosphate

Größe Preis ($) Menge Verfügbarkeit
1g 29,60
5g 53,00
25g 139,00
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

O-(7-Aza-1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate, 99%

MDL
MFCD00274639

Chemische Eigenschaften

Formel
C10H15F6N6OP
Molmasse
380.23
Schmelzpunkt
ca 185° dec.
Löslichkeit
Soluble in acetonitrile. Insoluble in water.

Anwendungen

O-(7-Aza-1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate is a coupling reagent and used as an additive in peptide synthesis., It is also involved efficiently to speed up the coupling process and reduces the loss of chiral integrity.

Bemerkungen

Moisture sensitive. Incompatible with oxidizing agents and highly acidic or alkaline materials.

Literaturverweise

Yoshida, M.; Sasahara, K. I.; Doi, T. Total synthesis of cyclodepsipeptide spiruchostatin A on silyl-linked polymer-support. Tetrahedron 2015, 71 (40), 7647-7653.

Xie, Y.; Yu, C.; Li, T.; Tu, S.; Yao, C. An NHC-Catalyzed In Situ Activation Strategy to β-Functionalize Saturated Carboxylic Acid: An Enantioselective Formal [3+ 2] Annulation for Spirocyclic Oxindolo-γ-butyrolactones. Chem. Eur. J. 2015, 21 (14), 5355-5359.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H228-H315-H319-H335-H303

Flammable solid. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. May be harmful if swallowed.

Sicherheitshinweise: P210-P261-P280-P240-P241-P305+P351+P338-P304+P340-P362-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Gefahrenklasse
4.1
Verpackungsgruppe
II
Harmonized Tariff Code
2933.99
TSCA
No
RTECS
XZ5633000

Empfohlen

  • A10807

    1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride, 98+%
  • A11801

    N-Ethyldiisopropylamine, 99%
  • A12245

    Succinic anhydride, 99%
  • A13016

    4-(Dimethylamino)pyridine, 99%
  • A14688

    1,1'-Carbonyldiimidazole, 97%

Kürzlich angesehen

Chemikalien

Life science

Metalle und Stoffe

Katalysatoren

Forschungs- und Laborbedarf