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202982-70-5 - 3-Chloro-5-fluorophenol, 98% - H26195 - Alfa Aesar

H26195 3-Chloro-5-fluorophenol, 98%

CAS-Nummer
202982-70-5
Synonyme

Größe Preis ($) Menge Verfügbarkeit
1g 83,00
5g 246,00
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3-Chloro-5-fluorophenol, 98%

MDL
MFCD00042212
EINECS
None

Chemische Eigenschaften

Formel
C6H4ClFO
Molmasse
146.55
Brechungsindex
1.537
Löslichkeit
Immiscible with water.

Anwendungen

3-Chloro-5-fluorophenol is used as an intermediate in organic synthesis. It plays an important role in the preparation of substituted amides as antagonists and/or inverse agonists of cannabinoid-1 receptor, substituted N-(arylmethyl)aryloxy arylcarboxamide and heteroarylcarboxamide antagonists for the PGE2 receptor EP4 for the treatment of pain, inflammation, osteoarthritis, and rheumatoid arthritis.

Bemerkungen

Incompatible with strong oxidizing agents.

Literaturverweise

Huang, H.; Ji, H.; Li, H.; Jing, Q.; Labby, K. J.; Martasek, P.; Roman, L. J.; Poulos, T. L.; Silverman, R. B. Selective Monocationic Inhibitors of Neuronal Nitric Oxide Synthase. Binding Mode Insights from Molecular Dynamics Simulations. J. Am. Chem. Soc. 2012, 134 (28), 11559-11572.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H302-H312-H314-H318

Harmful if swallowed. Harmful in contact with skin. Causes severe skin burns and eye damage. Causes serious eye damage.

Sicherheitshinweise: P273-P280-P303+P361+P353-P305+P351+P338-P310a

Avoid release to the environment. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Weitere Referenzen

Gefahrenklasse
8
Verpackungsgruppe
III
Harmonized Tariff Code
2908.19
TSCA
No

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