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2-Bromo-4-chloro-6-fluoroanisole, 97% - H26375 - Alfa Aesar

H26375 2-Bromo-4-chloro-6-fluoroanisole, 97%

CAS-Nummer
Synonyme

Größe Preis ($) Menge Verfügbarkeit
1g 37,70
5g 112,00
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2-Bromo-4-chloro-6-fluoroanisole, 97%

MDL
MFCD04115953

Chemische Eigenschaften

Formel
C7H5BrClFO
Molmasse
239.47
Löslichkeit
Insoluble in water.

Anwendungen

An Acetanilide and Anisole derivative metabolite by liver. It is used to produce (5-fluoro-2-methoxy-phenyl)-(4-trifluoromethyl-phenyl)-methanone by reaction with 4-trifluoromethyl-benzonitrile. The reaction occurs with reagent Mg and solvent diethyl ether with other condition of heating for 2 hours. The yield is about 82%.

Bemerkungen

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Literaturverweise

Karsten Menzel,; Fouzia Machrouhi,; Matthew Bodenstein,; Anthony Alorati,; Cameron Cowden,; Andrew W. Gibson,; Brian Bishop,; Norihiro Ikemoto,; Todd D. Nelson,; Michael H. Kress,; Doug E. Frantz. Process Development of a Potent Bradykinin 1 Antagonist. Org. Process Res. Dev2009, 13(3),519-524.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P260u-P201-P280a-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves and eye/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Harmonized Tariff Code
2909.30
TSCA
No

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